19 October, 2025
nhs-issues-urgent-alert-on-ibuprofen-and-ginkgo-biloba-risk

The National Health Service (NHS) has issued a warning regarding the potential risks of combining the widely-used painkiller ibuprofen with the natural supplement Ginkgo biloba. This combination may significantly increase the risk of serious complications, particularly bleeding. While ibuprofen is a common medication available over the counter in supermarkets and pharmacies throughout the UK, awareness of its interactions with certain supplements is crucial for consumer safety.

Ibuprofen is an effective non-steroidal anti-inflammatory drug (NSAID) that alleviates pain and reduces inflammation. It is commonly used for various conditions, including back pain, period pain, toothache, and symptoms associated with colds and flu, including COVID-19. Most individuals typically take between three to four doses daily, depending on the severity of their symptoms. The NHS recommends taking ibuprofen with food or milk to minimize stomach irritation, although it may take longer to become effective when taken this way.

Risks of Combining Ibuprofen with Supplements

The NHS has clarified that while it is generally safe to combine ibuprofen with medications such as paracetamol or codeine, caution is advised when considering supplements. Specifically, the NHS highlights that taking Ginkgo biloba alongside ibuprofen can elevate the likelihood of bleeding due to both substances affecting blood clotting. Ginkgo biloba is often taken to enhance cognitive function and improve blood circulation, but this dual effect can lead to serious health risks.

Notably, the NHS warns that there is insufficient information regarding the safety of other herbal remedies when used with ibuprofen. As these supplements are not subjected to the same rigorous testing as prescription medications, consumers should remain vigilant.

Common and Serious Side Effects of Ibuprofen

While ibuprofen is generally safe for most people, it can cause side effects. Commonly reported issues include headaches, dizziness, nausea, and indigestion, affecting approximately 1 in 100 users. If more severe symptoms occur, immediate medical attention is advised. Serious side effects may include:

– Black or bloody stools, indicating potential gastrointestinal bleeding
– Swelling in the ankles or blood in urine, which could signal kidney problems
– Severe chest or stomach pain, possibly indicating a perforation
– Difficulty breathing or exacerbated asthma symptoms
– Severe headaches accompanied by fever or a stiff neck, suggesting possible meningitis
– Visual disturbances or hallucinations

In rare instances, individuals may experience an allergic reaction to ibuprofen, known as anaphylaxis. Users are encouraged to report any adverse effects through the Yellow Card safety scheme, which helps monitor medication safety.

As with any medication, it is essential for consumers to consult healthcare professionals before making changes to their medication or supplement routines. The NHS continues to emphasize the importance of using medications safely and effectively, particularly in the context of combining various treatments.