UPDATE: In an inspiring collaboration, USC and UCLA are joining forces to tackle some of society’s most pressing challenges, proving that fierce rivals on the football field can be invaluable partners off it. This initiative, announced on November 24, 2025, highlights how both institutions are leveraging their strengths to drive innovation in medicine, technology, and community service.
The partnership showcases a range of groundbreaking efforts, including the world’s first bladder transplant conducted at Ronald Reagan UCLA Medical Center. This historic surgery was co-led by Inderbir Gill, from USC, and Nima Nassiri from UCLA, marking a major leap in urologic surgery that promises to improve the quality of life for patients suffering from debilitating conditions.
“Collaboration is the key to innovation,” said Gill. “Together, we are not just advancing science; we are saving lives.” The patient from this pioneering surgery is now over six months post-operation and doing exceptionally well, showcasing the potential for future procedures.
Additionally, a new $6.5 million grant awarded to USC, UCLA, and Cedars-Sinai aims to extend the “healthspan” of older adults by focusing on practical treatments that halt disease progression. This initiative is part of a national consortium that spans 15 institutions, emphasizing the urgency of addressing aging as a public health challenge.
Facing a crisis of homelessness, with an estimated 47,000 people living unsheltered in Los Angeles County, a collaborative project called PATHS is using mobile surveys to assess the needs of this vulnerable population. With the support of the NIH, researchers are gathering essential data to inform policies that could change lives.
In the wake of devastating wildfires in January, the USC Lusk Center for Real Estate and the UCLA Ziman Center are co-developing a recovery plan to guide rebuilding efforts. Their report, “Project Recovery,” brings together over 100 experts to ensure Los Angeles is better equipped for future disasters.
The partnership extends into the realm of mental health, where the PRECOG project aims to develop automated tools for detecting depression and suicidal ideation. This research is vital, as depression is often a hidden threat, and timely intervention can save lives.
As Kate Weber from USC Dornsife Public Exchange states, “ShadeLA is stronger because USC and UCLA are working side by side.” This initiative aims to increase shade in high-heat neighborhoods, a crucial strategy as climate change forecasts an increase in extreme heat days by 31% by 2050.
These collaborations are not only focused on high-stakes medical advancements but also on community engagement and cultural heritage. The Immersive Technologies and Cultural Heritage symposium recently showcased projects that blend technology and art, fostering creativity and innovation across disciplines.
The E-Conquest gaming tournament is another testament to their collaboration, where students compete in an annual video game contest, demonstrating that friendly rivalry can lead to shared experiences and community spirit.
As both universities continue to break new ground, they reaffirm their commitment to serving Los Angeles and the world. The upcoming USC vs. UCLA football game will undoubtedly reignite their rivalry on the field, but the true impact of their partnership is felt beyond the gridiron, shaping a better future for all.
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